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© 2019 Amberstone Biosciences

Platform Technology
 
Our innovative microfluidic based single cell platform technology (AmberFlow    ) integrates proprietary systems and methods with our deep understanding of biology. It unlocks the power of single cell function analysis in a tunable microenvironment to enable the highly efficient isolation of rare high-quality candidates while delivering rich information. 
  • Any cell sample source such as primary B cells and T cells. A variety of engineered cell libraries. 
  • Versatile assays. Direct functional analysis. Binder screening. Cross-species reactivity. Isoform specificity. 
  • In-depth screening (e.g., whole immune repertoire), while delivering greater diversity and rich information to enable IP protection and differentiation from competitors. 
  • Fast expression and function validation in parallel with sequencing, effectively circumventing conventional lengthy processes involving high-throughput sequencing, DNA synthesis, individual cloning, protein expression and then validation. 
  • Fast turnaround. Weeks, not months.
 
Pipeline
We are developing several first-in-class immunotherapeutic pipeline assets with significant differentiation.
Publications
Functional TCR T cell screening using single-cell droplet microfluidics.
Segaliny A., et al.  Lab Chip,  2018, 18:3733-3749.
   
DOI: 10.1039/c8lc00818c
Highlight by Science Magazine:  
https://stm.sciencemag.org/content/10/468/eaav9144
TM